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Literature summary for 2.7.1.105 extracted from

  • Baltrusch, S.; Schmitt, H.; Brix, A.; Langer, S.; Lenzen, S.
    Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and the chemical activator LY2121260 (2012), Biochem. Pharmacol., 83, 1300-1306.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
transfection of RINm5F cell Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
bifunctional 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
-

General Information

General Information Comment Organism
physiological function is an antagonist of glucokinase inhibition by the competitive glucokinase inhibitor mannoheptulose at increasing glucose concentrations. In combination with chemical activator LY2121260, the enzyme shows additive activation of glucokinase Rattus norvegicus