Any feedback?
Literature summary for 2.7.1.1 extracted from
- Molecular cloning and functional characterization of a hexokinase from the oriental river prawn Macrobrachium nipponense in response to hypoxia (2017), Int. J. Mol. Sci., 18, 1256 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli BL21 (DE3) | Macrobrachium nipponense |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Macrobrachium nipponense |  |
| diphosphate | - |
Macrobrachium nipponense | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.045 | - |
D-glucose | pH 8.0, 30°C | Macrobrachium nipponense | |
| 0.88 | - |
ATP | pH 8.0, 30°C | Macrobrachium nipponense | |
| 79 | - |
D-fructose | pH 8.0, 30°C | Macrobrachium nipponense | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 49720 | - |
calculated from sequence | Macrobrachium nipponense |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Macrobrachium nipponense | A0A220NLA7 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Macrobrachium nipponense |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| gill | moderate activity | Macrobrachium nipponense | - |
| heart | low activity | Macrobrachium nipponense | - |
| hepatopancreas | high activity | Macrobrachium nipponense | - |
| intestine | low activity | Macrobrachium nipponense | - |
| muscle | high activity | Macrobrachium nipponense | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-fructose | - |
Macrobrachium nipponense | ADP + D-fructose 6-phosphate | - |
? | |
| ATP + D-glucose | - |
Macrobrachium nipponense | ADP + D-glucose 6-phosphate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.46 | - |
- |
Macrobrachium nipponense |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.011 | - |
diphosphate | pH 8.0, 30°C | Macrobrachium nipponense | |
| 0.76 | - |
ADP | pH 8.0, 30°C | Macrobrachium nipponense | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | key glycolytic enzyme. The enzyme is a key factor that increases the anaerobic rate, and is probably involved in the HIF-1 pathway related to highly active metabolism during hypoxia | Macrobrachium nipponense |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
