Application | Comment | Organism |
---|---|---|
medicine | hexokinase is distributed in the worm extensively as well as in liver tissue and serum from infected rats. High-level specific IgG1 and IgG2a are induced in rats by immunization with recombinant enzyme. The enzymatic activity of hexokinase is suppressed by the antibodies in vitro, and the survival of Clonorchis sinensis is inhibited by the antibodies in vivo and in vitro | Clonorchis sinensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clonorchis sinensis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | hexokinase is distributed in the worm extensively as well as in liver tissue and serum from Clonorchis sinensis infected rats | Clonorchis sinensis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose | - |
Clonorchis sinensis | ADP + D-fructose 6-phosphate | 16.6% of the activity with ATP | ? | |
ATP + D-glucose | - |
Clonorchis sinensis | ADP + D-glucose 6-phosphate | - |
? | |
ATP + D-mannose | - |
Clonorchis sinensis | ADP + D-mannose 6-phosphate | 97% of the activity with ATP | ? | |
CTP + D-glucose | - |
Clonorchis sinensis | CDP + D-glucose 6-phosphate | 18% of the activity with ATP | ? | |
GTP + D-glucose | - |
Clonorchis sinensis | GDP + D-glucose 6-phosphate | 14% of the activity with ATP | ? | |
ITP + D-glucose | - |
Clonorchis sinensis | IDP + D-glucose 6-phosphate | 35% of the activity with ATP | ? | |
TTP + D-glucose | - |
Clonorchis sinensis | TDP + D-glucose 6-phosphate | 21% of the activity with ATP | ? | |
UTP + D-glucose | - |
Clonorchis sinensis | UDP + D-glucose 6-phosphate | 13% of the activity with ATP | ? |