Protein Variants | Comment | Organism |
---|---|---|
D217H | about 7% of wild-type activity | Eimeria tenella |
N216K | about 2% of wild-type activity | Eimeria tenella |
S159P | complete loss of activity | Eimeria tenella |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
mangiferin | - |
Eimeria tenella | |
quercetin | - |
Eimeria tenella |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.67 | - |
D-glucose | wild-type, pH 9.0, 36°C | Eimeria tenella | |
5.66 | - |
2-deoxy-D-glucose | wild-type, pH 9.0, 36°C | Eimeria tenella | |
13.76 | - |
D-fructose | wild-type, pH 9.0, 36°C | Eimeria tenella | |
16.9 | - |
D-glucose | mutant D217H, pH 9.0, 36°C | Eimeria tenella | |
25.41 | - |
D-mannose | wild-type, pH 9.0, 36°C | Eimeria tenella | |
26.4 | - |
D-glucose | mutant N216K, pH 9.0, 36°C | Eimeria tenella |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
- |
Eimeria tenella |
50500 | - |
- |
Eimeria tenella |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Eimeria tenella | A0A172WCE4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
oocyte | - |
Eimeria tenella | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2-deoxy-D-glucose | - |
Eimeria tenella | ADP + 2-deoxy-D-glucose 6-phosphate | - |
? | |
ATP + D-fructose | - |
Eimeria tenella | ADP + D-fructose 6-phosphate | - |
? | |
ATP + D-glucose | - |
Eimeria tenella | ADP + D-glucose 6-phosphate | - |
? | |
ATP + D-mannose | poor substrate | Eimeria tenella | ADP + D-mannose 6-phosphate | - |
? | |
additional information | no substrate: D-galactose | Eimeria tenella | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50500, calculated, x * 50000, SDS-PAGE | Eimeria tenella |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
36 | - |
- |
Eimeria tenella |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.025 | - |
D-mannose | wild-type, pH 9.0, 36°C | Eimeria tenella | |
1.5 | - |
D-fructose | wild-type, pH 9.0, 36°C | Eimeria tenella | |
10.8 | - |
D-glucose | mutant N216K, pH 9.0, 36°C | Eimeria tenella | |
33.7 | - |
2-deoxy-D-glucose | wild-type, pH 9.0, 36°C | Eimeria tenella | |
39.7 | - |
D-glucose | mutant D217H, pH 9.0, 36°C | Eimeria tenella | |
219 | - |
D-glucose | wild-type, pH 9.0, 36°C | Eimeria tenella |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9 | - |
- |
Eimeria tenella |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Eimeria tenella | calculated | - |
5.7 |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.007 | - |
pH 9.0, 36°C | Eimeria tenella | quercetin | |
0.086 | - |
pH 9.0, 36°C | Eimeria tenella | mangiferin |