Literature summary for 2.7.1.1 extracted from

Tjhin, E.T.; Staines, H.M.; van Schalkwyk, D.A.; Krishna, S.; Saliba, K.J.
Studies with the Plasmodium falciparum hexokinase reveal that PfHT limits the rate of glucose entry into glycolysis (2013), FEBS Lett., 587, 3182-3187.

Search for more literature for 2.7.1.1

Inhibitors

Inhibitors	Comment	Organism	Structure
2-deoxy-D-glucose	compound is nearly 2fold less toxic Plasmodium falciparum lines overexpressing hexokinase compared with control parasites. Although catalytic activity is higher in in overexpressing cells, they accumulate phospho-2-deoxy-D-glucose at the same rate as control parasites	Plasmodium falciparum

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	a green fluorescent protein-labelled hexokinase shows the GFP fluorescence diffusely throughout the cytosol	Plasmodium falciparum	5829	-

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	-	-	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)