Organism | UniProt | Comment | Textmining |
---|---|---|---|
Helicoverpa armigera | A0A0P0I1H5 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pupa | expression and activity levels are significantly increased in nondiapause-destined pupae compared with those of diapause-destined pupae | Helicoverpa armigera | - |
General Information | Comment | Organism |
---|---|---|
physiological function | downregulation of activity reduces cell viability and delays pupaldevelopment by reducing metabolic activity and increasing reactive oxygen species activity. The transcription factors CREB, c-Myc, and POU are specifically binding the hexokinase gene promoter and regulating its activity. POU and c-Myc are specific transcription factors for hexokinase expression, whereas CREB is nonspecific. Low ecdysone levels in diapause-destined individuals lead to low POU and c-Myc expression levels, ultimately repressing hexokinase expression and inducing entry into diapause or lifespan extension | Helicoverpa armigera |