Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glucokinase regulatory protein | binds glucokinase in the nucleus and inhibits its activity | Canis lupus familiaris | |
glucokinase regulatory protein | binds glucokinase in the nucleus and inhibits its activity | Felis catus | |
glucokinase regulatory protein | binds glucokinase in the nucleus and inhibits its activity | Rattus norvegicus | |
additional information | not inhibited by D-glucose-6-phosphate | Canis lupus familiaris | |
additional information | not inhibited by D-glucose-6-phosphate | Felis catus | |
additional information | not inhibited by D-glucose-6-phosphate | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | glucokinase becomes active when it is released from glucokinase regulatory protein and translocates to the cytosol | Rattus norvegicus | 5829 | - |
cytosol | glucokinase becomes active when it is released from glucokinase regulatory protein and translocates to the cytosol | Canis lupus familiaris | 5829 | - |
cytosol | glucokinase becomes active when it is released from glucokinase regulatory protein and translocates to the cytosol | Felis catus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Felis catus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
liver | - |
Canis lupus familiaris | - |
liver | - |
Felis catus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-glucose | - |
Rattus norvegicus | ADP + D-glucose 6-phosphate | - |
? | |
ATP + D-glucose | - |
Canis lupus familiaris | ADP + D-glucose 6-phosphate | - |
? | |
ATP + D-glucose | - |
Felis catus | ADP + D-glucose 6-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glucokinase | - |
Rattus norvegicus |
glucokinase | - |
Canis lupus familiaris |
glucokinase | - |
Felis catus |
HK4 | - |
Rattus norvegicus |
HK4 | - |
Canis lupus familiaris |
HK4 | - |
Felis catus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus | |
ATP | - |
Canis lupus familiaris | |
ATP | - |
Felis catus |
General Information | Comment | Organism |
---|---|---|
physiological function | glucokinase acts as a hepatic glucose sensor that permits hepatic metabolism to respond appropriately to changes in plasma glucose concentrations | Rattus norvegicus |
physiological function | glucokinase acts as a hepatic glucose sensor that permits hepatic metabolism to respond appropriately to changes in plasma glucose concentrations | Canis lupus familiaris |
physiological function | glucokinase acts as a hepatic glucose sensor that permits hepatic metabolism to respond appropriately to changes in plasma glucose concentrations | Felis catus |