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Literature summary for 2.7.1.1 extracted from

  • Medrano, A.; Garcia-Gil, N.; Ramio, L.; Montserrat Rivera, M.; Fernandez-Novell, J.M.; Ramirez, A.; Pena, A.; Dolors Briz, M.; Pinart, E.; Concha, I.I.; Bonet, S.; Rigau, T.; Rodriguez-Gil, J.E.
    Hexose-specificity of hexokinase and ADP-dependence of pyruvate kinase play important roles in the control of monosaccharide utilization in freshly diluted boar spermatozoa (2006), Mol. Reprod. Dev., 73, 1179-1194.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + D-glucose Sus scrofa the presence of 0.5 mM glucose induced total hexokinase activity in supernatants from sperm extracts of 1.7 mIU/mg protein, while the same concentration of both fructose, mannose, and sorbitol induced total hexokinase activity from 0.3 mIU/mg protein to 0.60 IU/mg protein. Diluted boar sperm from fresh ejaculates phosphorylates glucose through the hexokinase step much more efficiently than fructose or mannose. This difference facilitates a much more rapid intake of glucose into glycolysis than the other sugars ADP + D-glucose 6-phosphate
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Organism

Organism UniProt Comment Textmining
Sus scrofa
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boar
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Source Tissue

Source Tissue Comment Organism Textmining
sperm the presence of 0.5 mM glucose induces total hexokinase activity in supernatants from sperm extracts of 1.7 mIU/mg protein, while the same concentration of both fructose, mannose, and sorbitol induces total hexokinase activity from 0.3 mIU/mg protein to 0.60 IU/mg protein. Diluted boar sperm from fresh ejaculates phosphorylates glucose through the hexokinase step much more efficiently than fructose or mannose. This difference facilitates a much more rapid intake of glucose into glycolysis than the other sugars Sus scrofa
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-glucose the presence of 0.5 mM glucose induced total hexokinase activity in supernatants from sperm extracts of 1.7 mIU/mg protein, while the same concentration of both fructose, mannose, and sorbitol induced total hexokinase activity from 0.3 mIU/mg protein to 0.60 IU/mg protein. Diluted boar sperm from fresh ejaculates phosphorylates glucose through the hexokinase step much more efficiently than fructose or mannose. This difference facilitates a much more rapid intake of glucose into glycolysis than the other sugars Sus scrofa ADP + D-glucose 6-phosphate
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?