Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-glucose | at high concentrations; inhibits hexokinase III | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | in granulocytes and erythrocytes most of the hexokinase activity is found in the cytosol | Homo sapiens | 5829 | - |
particle-bound | in lymphocytes and platelets most of the hexokinase activity is particle-bound | Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose + ATP | Homo sapiens | glycolytic enzyme | D-glucose 6-phosphate + ADP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
hexokinase types I and III | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | contains only hexokinase I | Homo sapiens | - |
erythrocyte | contains a multibanded type I hexokinase | Homo sapiens | - |
granulocyte | 70-80% hexokinase III, 20-30% hexokinase I | Homo sapiens | - |
lymphocyte | contains mainly hexokinase I and a minor amount of hexokinase III in the soluble fraction, less than 10% | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose + ATP | - |
Homo sapiens | ADP + D-glucose 6-phosphate | - |
? | |
D-glucose + ATP | glycolytic enzyme | Homo sapiens | D-glucose 6-phosphate + ADP | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |