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Literature summary for 2.6.1.95 extracted from

  • Clausnitzer, D.; Piepersberg, W.; Wehmeier, U.F.
    The oxidoreductases LivQ and NeoQ are responsible for the different 6-modifications in the aminoglycosides lividomycin and neomycin (2011), J. Appl. Microbiol., 111, 642-651.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Streptomyces fradiae

Organism

Organism UniProt Comment Textmining
Streptomyces fradiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information NeoB is a bifunctional enzyme that also catalyses the NH2 group transfer at the 6'''-position Streptomyces fradiae ?
-
?
neomycin C + 2-oxoglutarate
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Streptomyces fradiae 6'''-hydroxyneomycin C + L-glutamate
-
?

Synonyms

Synonyms Comment Organism
neoB
-
Streptomyces fradiae