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Literature summary for 2.6.1.79 extracted from

  • Graindorge, M.; Giustini, C.; Kraut, A.; Moyet, L.; Curien, G.; Matringe, M.
    Three different classes of aminotransferases evolved prephenate aminotransferase functionality in arogenate-competent microorganisms (2014), J. Biol. Chem., 289, 3198-3208.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
prephenate cosubstrate L-glutamate, pH 8.0, 30°C Streptomyces avermitilis
0.021
-
prephenate cosubstrate N-succinyl-L-2,6-diaminoheptanedioate, pH 8.0, 30°C Streptomyces avermitilis
0.1
-
prephenate pH 8.0, 30°C Sinorhizobium meliloti
0.13
-
prephenate pH 8.0, 30°C Synechocystis sp.

Organism

Organism UniProt Comment Textmining
Sinorhizobium meliloti Q02635 cf. EC 2.6.1.1
-
Streptomyces avermitilis Q82IK5 cf. EC 2.6.1.17
-
Streptomyces avermitilis DSM 46492 Q82IK5 cf. EC 2.6.1.17
-
Synechocystis sp. P54691 cf. EC 2.6.1.42
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prephenate + L-glutamate
-
Streptomyces avermitilis L-arogenate + 2-oxoglutarate
-
?
prephenate + L-glutamate
-
Sinorhizobium meliloti L-arogenate + 2-oxoglutarate
-
?
prephenate + L-glutamate
-
Synechocystis sp. L-arogenate + 2-oxoglutarate
-
?
prephenate + L-glutamate
-
Streptomyces avermitilis DSM 46492 L-arogenate + 2-oxoglutarate
-
?
prephenate + N-succinyl-L-2,6-diaminoheptanedioate
-
Streptomyces avermitilis L-arogenate + N-succinyl-2-amino-6-oxoheptanedioate
-
?
prephenate + N-succinyl-L-2,6-diaminoheptanedioate
-
Streptomyces avermitilis DSM 46492 L-arogenate + N-succinyl-2-amino-6-oxoheptanedioate
-
?

Synonyms

Synonyms Comment Organism
aatA
-
Sinorhizobium meliloti
aspartate aminotransferase A
-
Sinorhizobium meliloti
AspB2
-
Streptomyces avermitilis
IlvE
-
Synechocystis sp.

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
24
-
prephenate cosubstrate N-succinyl-L-2,6-diaminoheptanedioate, pH 8.0, 30°C Streptomyces avermitilis
43
-
prephenate pH 8.0, 30°C Sinorhizobium meliloti
54
-
prephenate cosubstrate L-glutamate, pH 8.0, 30°C Streptomyces avermitilis
60
-
prephenate pH 8.0, 30°C Synechocystis sp.