Protein Variants | Comment | Organism |
---|---|---|
E64G | the naturally occurring mutation in rat KAT I results in dramatically impaired kynurenic acid synthesis and in an associated spontaneously hypertensive phenotype | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
brain | - |
Rattus norvegicus | - |
kidney | - |
Homo sapiens | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + 2-oxobutyrate | - |
Homo sapiens | kynurenic acid + 2-aminobutanoate + H2O | - |
? | |
L-kynurenine + 2-oxobutyrate | - |
Rattus norvegicus | kynurenic acid + 2-aminobutanoate + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KAT II | identical with alpha-aminoadipate aminotransferase | Homo sapiens |
KAT II | identical with alpha-aminoadipate aminotransferase | Rattus norvegicus |
type II kynurenine aminotransferase | - |
Homo sapiens |
type II kynurenine aminotransferase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Homo sapiens | |
pyridoxal 5'-phosphate | - |
Rattus norvegicus |