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Literature summary for 2.6.1.64 extracted from

  • Cooper, A.J.; Pinto, J.T.; Krasnikov, B.F.; Niatsetskaya, Z.V.; Han, Q.; Li, J.; Vauzour, D.; Spencer, J.P.
    Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase (2008), Arch. Biochem. Biophys., 474, 72-81.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
recombinant
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-S-L-cysteinyl-L-DOPA + 4-(methylsulfanyl)-2-oxobutanoate
-
Homo sapiens ?
-
?
5-S-L-cysteinyldopamine + 4-(methylsulfanyl)-2-oxobutanoate transamination of 5 mM 5-S-Lcysteinyldopamine with 1 mM 4-(methylsulfanyl)-2-oxobutanoateat pH 7.4 is about 0.07% the rate at which the enzyme catalyzes transamination between 20 mM L-phenylalanine and 5 mM alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
L-3-(1-naphthyl)alanine + 4-(methylsulfanyl)-2-oxobutanoate about 0.2% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
L-3-(2-naphthyl)alanine + 4-(methylsulfanyl)-2-oxobutanoate about 0.5% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
L-DOPA + 4-(methylsulfanyl)-2-oxobutanoate about 0.02% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
L-kynurenine + 4-(methylsulfanyl)-2-oxobutanoate about 23.6% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
L-phenylalanine + 4-(methylsulfanyl)-2-oxobutanoate
-
Homo sapiens ?
-
?
L-tyrosine + 4-(methylsulfanyl)-2-oxobutanoate about 9% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
additional information recombinant human glutamine transaminase K exhibits broad specificity both as an aminotransferase and as a cysteine S-conjugate beta-lyase Homo sapiens ?
-
?
phenylpyruvate + L-glutamine about 64% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
phenylpyruvate + L-leucine about 25% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
phenylpyruvate + L-methionine about 30% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
S-(1,1,2,2-tetrafluoroethyl)-L-cysteine + 4-(methylsulfanyl)-2-oxobutanoate about 63% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
S-(1,2-dichlorovinyl)-L-cysteine + 4-(methylsulfanyl)-2-oxobutanoate about 13% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate Homo sapiens ?
-
?
Se-methyl-L-selenocysteine + 4-(methylsulfanyl)-2-oxobutanoate
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
glutamine transaminase K
-
Homo sapiens
GTK
-
Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
-
Homo sapiens