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Literature summary for 2.6.1.50 extracted from

  • Yokoyama, K.; Kudo, F.; Kuwahara, M.; Inomata, K.; Tamegai, H.; Eguchi, T.; Kakinuma, K.
    Stereochemical recognition of doubly functional aminotransferase in 2-deoxystreptamine biosynthesis (2005), J. Am. Chem. Soc., 127, 5869-5874.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Niallia circulans enzyme is also involved in transamination of a putative aminoketone intermediate in 2-deoxystreptamine synthesis ?
-
?
additional information Niallia circulans SANK 72073 enzyme is also involved in transamination of a putative aminoketone intermediate in 2-deoxystreptamine synthesis ?
-
?

Organism

Organism UniProt Comment Textmining
Niallia circulans
-
-
-
Niallia circulans SANK 72073
-
-
-

Reaction

Reaction Comment Organism Reaction ID
L-glutamine + 2,4,6/3,5-pentahydroxycyclohexanone = 2-oxoglutaramate + 1-amino-1-deoxy-scyllo-inositol mechanism, enzyme distinguishes the enantiotopic amino groups of 2-deoxystreptamine but accepts both enantiomers of 2-deoxy-scyllo-inosose to give a racemic product Niallia circulans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-deoxy-scyllo-inosose + L-glutamine accepts both enantiomers to give a racemic product Niallia circulans 2-deoxy-scyllo-inosamine + 2-oxoglutaramate
-
r
2-deoxy-scyllo-inosose + L-glutamine accepts both enantiomers to give a racemic product Niallia circulans SANK 72073 2-deoxy-scyllo-inosamine + 2-oxoglutaramate
-
r
additional information enzyme is also involved in transamination of a putative aminoketone intermediate in 2-deoxystreptamine synthesis Niallia circulans ?
-
?
additional information enzyme is also involved in transamination of a putative aminoketone intermediate in 2-deoxystreptamine synthesis Niallia circulans SANK 72073 ?
-
?

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Niallia circulans