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Literature summary for 2.6.1.5 extracted from

  • Kaledin, V.; Ilnitskaya, S.; Popova, N.; Koval, O.; Pyshnaya, I.; Gulyaeva, L.
    Induction of tyrosine aminotransferase in mice is inhibited by the activated metabolites of ortho-aminoazotoluene (2016), Russ. J. Genet. Appl. Res., 6, 91-98 .
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tyrosine + 2-oxoglutarate Mus musculus
-
4-hydroxyphenylpyruvate + L-glutamate
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tyrosine + 2-oxoglutarate
-
Mus musculus 4-hydroxyphenylpyruvate + L-glutamate
-
?

Synonyms

Synonyms Comment Organism
TAT
-
Mus musculus
tyrosine aminotransferase
-
Mus musculus

Expression

Organism Comment Expression
Mus musculus the enzyme activity is induced by the intraperitoneal injection of hydrocortisone in a dose of 50 mg/kg or dexamethasone phosphate in a dose of 5 mg/kg of body weight. Ortho-aminoazotoluene decreases enzyme induction by hydrocortisone by more than 40% up