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Literature summary for 2.6.1.45 extracted from

  • Karsten, W.E.; Cook, P.F.
    Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum (2009), Biochim. Biophys. Acta, 1790, 575-580.
    View publication on PubMed
Search for more literature for 2.6.1.45

Cloned(Commentary)

Cloned (Comment) Organism
-
 Hyphomicrobium methylovorum

Inhibitors

Inhibitors Comment Organism Structure
D-serine competitive inhibition with L-serine Hyphomicrobium methylovorum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43880
-
 calculated from amino acid sequence Hyphomicrobium methylovorum

Organism

Organism UniProt Comment Textmining
Hyphomicrobium methylovorum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Hyphomicrobium methylovorum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-serine + glyoxylate
-
 Hyphomicrobium methylovorum 3-hydroxypyruvate + glycine
-
 r

Subunits

Subunits Comment Organism
homotetramer
-
 Hyphomicrobium methylovorum

Synonyms

Synonyms Comment Organism
serine-glyoxylate aminotransferase
-
 Hyphomicrobium methylovorum
SGAT
-
 Hyphomicrobium methylovorum

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate contains 1 mol of pyridoxal 5'-phosphate per subunit Hyphomicrobium methylovorum

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4
-
 D-serine
-
 Hyphomicrobium methylovorum