Application | Comment | Organism |
---|---|---|
medicine | - |
Homo sapiens |
Cloned (Comment) | Organism |
---|---|
AGXT cDNA cloned, AGXT*LTM expressed as a GST-fusion protein in Escherichia coli BL21(RIL) and in Sf9 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amino-oxyacetic acid | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.36 | - |
glyoxylate | pH 7.4, 37°C, alanine as amino donor | Homo sapiens | |
14.9 | - |
L-alanine | pH 7.4, 37°C, glyoxylate as amino acceptor | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
peroxisome | - |
Homo sapiens | 5777 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine + glyoxylate | Homo sapiens | key role in the transamination/detoxification of glyoxylate | pyruvate + glycine | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human | - |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine + glyoxylate | - |
Homo sapiens | pyruvate + glycine | - |
ir | |
L-alanine + glyoxylate | key role in the transamination/detoxification of glyoxylate | Homo sapiens | pyruvate + glycine | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
AGXT | - |
Homo sapiens |