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Literature summary for 2.6.1.36 extracted from

  • Duan, X.; Li, Y.; Du, Q.; Huang, Q.; Guo, S.; Xu, M.; Lin, Y.; Liu, Z.; Xie, J.
    Mycobacterium lysine epsilon-aminotransferase is a novel alarmone metabolism related persister gene via dysregulating the intracellular amino acid level (2016), Sci. Rep., 6, 19695.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WQ77
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Mycobacterium tuberculosis H37Rv P9WQ77
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-

Synonyms

Synonyms Comment Organism
Rv3290c
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Mycobacterium tuberculosis

Expression

Organism Comment Expression
Mycobacterium tuberculosis in a hypoxia persistent model, enzyme expression is signifcantly upregulated up

General Information

General Information Comment Organism
physiological function in enzyme deletion mutants, the expression of transcriptional regulator leucine-responsive regulatory protein LrpA and the amino acids abundance are lowered. The persistence capacity of the deletion mutant is impaired upon norfloxacin exposure under nutrient starvation Mycobacterium tuberculosis