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Literature summary for 2.6.1.2 extracted from

  • Tabuchi, H.; Sugiyama, T.
    Cooverexpression of alanine aminotransferase 1 in Chinese hamster ovary cells overexpressing taurine transporter further stimulates metabolism and enhances product yield (2013), Biotechnol. Bioeng., 110, 2208-2215.
    View publication on PubMed

Application

Application Comment Organism
synthesis for synthesis of monoclonal antibodies in Chinese hamster ovary cells, cooverexpression of alanine aminotransferase in a taurine transporter-overexpressing host cell line gives a higher monoclonal anitbody yield in a shorter culture period. Forced cooverexpression of taurine transporter TAUT and ALT1 in results in a higher proliferation, with an ideal balance between cell viability and productivity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P24298
-
-

Source Tissue

Source Tissue Comment Organism Textmining
CHO cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
ALT1
-
Homo sapiens
GPT
-
Homo sapiens