Literature summary for 2.6.1.2 extracted from

Dahari, H.; Markatou, M.; Zeremski, M.; Haller, I.; Ribeiro, R.M.; Licholai, T.; Perelson, A.S.; Talal, A.H.
Early ribavirin pharmacokinetics, HCV RNA and alanine aminotransferase kinetics in HIV/HCV co-infected patients during treatment with pegylated interferon and ribavirin (2007), J. Hepatol., 47, 23-30.

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Application

Application	Comment	Organism
medicine	treatment of HIV/HCV co-infected patients with pegylated interferon and ribavirin. At week 1, serum HCV RNA levels and changes in alanine aminotransferase levels relative to baseline can identify likely responders better than plasma ribavirin levels. During the first four weeks of treatment, median plasma ribavirin levels and area under the ribavirin curve are significantly lower in sustained responders compared with nonresponders	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Homo sapiens	-	HIV/HCV co-infected patients	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
ALT	-	Homo sapiens

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Release 2023.1 (January 2023)