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Literature summary for 2.6.1.19 extracted from

  • Moschitto, M.J.; Silverman, R.B.
    Synthesis of (S)-3-amino-4-(difluoromethylenyl)-cyclopent-1-ene-1-carboxylic acid (OV329), a potent inactivator of gamma-aminobutyric acid aminotransferase (2018), Org. Lett., 20, 4589-4592 .
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
(1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid
-
 Homo sapiens
(S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid i.e. OV329, synthesis method, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-aminobutanoate + 2-oxoglutarate Homo sapiens
-
 succinate semialdehyde + L-glutamate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P80404
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-aminobutanoate + 2-oxoglutarate
-
 Homo sapiens succinate semialdehyde + L-glutamate
-
 ?

Synonyms

Synonyms Comment Organism
GABA-AT
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate PLP Homo sapiens