Protein Variants | Comment | Organism |
---|---|---|
K357A | no enzymic activity, even not by addition of exogenous pyridoxal 5-phosphate | Homo sapiens |
K357B | no enzymic activity, even not by addition of exogenous pyridoxal 5-phosphate | Homo sapiens |
K357N | no enzymic activity, even not by addition of exogenous pyridoxal 5-phosphate | Homo sapiens |
K357Q | no enzymic activity, even not by addition of exogenous pyridoxal 5-phosphate | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
x * 50000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Renatured (Comment) | Organism |
---|---|
apoenzyme reconstituted with exogenous pyridoxal 5-phosphate almost completely regains catalytic activity | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
17.5 | - |
pH 8.4, 25°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-aminobutanoate + 2-oxoglutarate | - |
Homo sapiens | 4-oxobutanoate + L-glutamate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, SDS-PAGE | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | K357 is involved in binding | Homo sapiens |