Literature summary for 2.6.1.19 extracted from

Jeon, S.G.; Bahn, J.H.; Jang, J.S.; Park, J.; Kwon, O.S.; Cho, S.W.; Choi, S.Y.
Human brain GABA transaminase tissue distribution and molecular expression (2000), Eur. J. Biochem., 267, 5601-5607.

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Inhibitors

Inhibitors	Comment	Organism	Structure
vigabatrin	-	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.11	-	2-oxoglutarate	25°C, pH 8.4	Homo sapiens
1.27	-	4-aminobutanoate	25°C, pH 8.4	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-aminobutanoate + 2-oxoglutarate	-	Homo sapiens	4-oxobutanoate + L-glutamate	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
1	-	vigabatrin	pH 8.4, 25°C	Homo sapiens

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Release 2023.1 (January 2023)