Any feedback?
Literature summary for 2.6.1.19 extracted from
- Comparison of the structural characteristics of the 4-aminobutyrate:2-oxoglutarate transaminases from rat and human brain, and of their affinities for certain inhibitors (1978), Biochim. Biophys. Acta, 522, 385-399.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Branched-chain fatty acids | - |
Homo sapiens | |
| Branched-chain fatty acids | - |
Rattus norvegicus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Homo sapiens | |
| additional information | - |
additional information | - |
Rattus norvegicus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 57000 | - |
2 * 57000, SDS-PAGE | Homo sapiens |
| 57000 | - |
2 * 57000, SDS-PAGE with or without DTT or urea | Rattus norvegicus |
| 105000 | - |
- |
Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
| brain | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2.5 | - |
38°C, pH 8.6 | Rattus norvegicus |
| 4.9 | - |
- |
Homo sapiens |
| 4.9 | - |
38°C, pH 8.6 | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-aminobutanoate + 2-oxoglutarate | - |
Homo sapiens | 4-oxobutanoate + L-glutamate | - |
r |  |
| 4-aminobutanoate + 2-oxoglutarate | - |
Rattus norvegicus | 4-oxobutanoate + L-glutamate | - |
r | |
| beta-alanine + 2-oxoglutarate | - |
Homo sapiens | malonic semialdehyde + L-glutamate | - |
r | |
| beta-alanine + 2-oxoglutarate | - |
Rattus norvegicus | malonic semialdehyde + L-glutamate | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 57000, SDS-PAGE | Homo sapiens |
| dimer | 2 * 57000, SDS-PAGE with or without DTT or urea | Rattus norvegicus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 55 | - |
rapid inactivation | Rattus norvegicus |
| 55 | - |
slow inactivation | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Homo sapiens |
| 8.5 | - |
- |
Rattus norvegicus |
| 8.5 | 8.6 | - |
Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
