Application | Comment | Organism |
---|---|---|
medicine | role in mitotic cell division and target for chemotherapeutic drug development | Homo sapiens |
medicine | role in mitotic cell division and target for chemotherapeutic drug development | Xenopus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-Aminohex-5-ynoic acid | dose-dependent inhibitor | Homo sapiens | |
4-Aminohex-5-ynoic acid | dose-dependent inhibitor | Xenopus sp. | |
additional information | no inhibition by diazonamide A and syndistatin | Homo sapiens | |
additional information | no inhibition by diazonamide A and syndistatin | Xenopus sp. |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
mitochondrion | - |
Xenopus sp. | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Xenopus sp. | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Hitrap Q anion exchange chromatography | Homo sapiens |
Hitrap Q anion exchange chromatography | Xenopus sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
egg | - |
Xenopus sp. | - |
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine + 2-oxoglutarate | - |
Homo sapiens | DELTA1-pyrroline-5-carboxylate + L-glutamate | - |
? | |
L-ornithine + 2-oxoglutarate | - |
Xenopus sp. | DELTA1-pyrroline-5-carboxylate + L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
OAT | - |
Homo sapiens |
OAT | - |
Xenopus sp. |
ornithine delta-amino transferase | - |
Homo sapiens |
ornithine delta-amino transferase | - |
Xenopus sp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Homo sapiens | |
pyridoxal 5'-phosphate | - |
Xenopus sp. |