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Literature summary for 2.6.1.1 extracted from

  • Zhou, S.L.; Stump, D.; Kiang, C.L.; Isola, L.M.; Berk, P.D.
    Mitochondrial aspartate aminotransferase expressed on the surface of 3T3-L1 adipocytes mediates saturable fatty acid uptake (1995), Proc. Soc. Exp. Biol. Med., 208, 263-270.
    View publication on PubMed
Search for more literature for 2.6.1.1

Cloned(Commentary)

Cloned (Comment) Organism
cloning of a liver cDNA fragment, nucleotides 1-419, into a plasmid for production of cRNA probes Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-
mitochondrion mitochondrial isoenzyme Rattus norvegicus 5739
-
plasma membrane
-
 Rattus norvegicus 5886
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
 x * 43000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-aspartate + 2-oxoglutarate Rattus norvegicus anti-enzyme antibodies selectively inhibit the uptake of oleate in 3T3-L1 adipocytes by 31-55%, but only poorly in fibroblasts, the antibodies have no effect on uptake of 2-deoxyglucose and octanoate oxaloacetate + L-glutamate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 mitochondrial isozyme mAspAT
-

Purification (Commentary)

Purification (Comment) Organism
mitochondrial isozyme Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
adipocyte differentiated from 3T3-L1 fibroblasts Rattus norvegicus
-
fibroblast 3T3-L1 cells, low activity Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate + 2-oxoglutarate
-
 Rattus norvegicus oxaloacetate + L-glutamate
-
 ?
L-aspartate + 2-oxoglutarate anti-enzyme antibodies selectively inhibit the uptake of oleate in 3T3-L1 adipocytes by 31-55%, but only poorly in fibroblasts, the antibodies have no effect on uptake of 2-deoxyglucose and octanoate Rattus norvegicus oxaloacetate + L-glutamate
-
 ?

Subunits

Subunits Comment Organism
? x * 43000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
AspAT
-
 Rattus norvegicus