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Literature summary for 2.5.1.9 extracted from

  • Ladenstein, R.; Fischer, M.; Bacher, A.
    The lumazine synthase/riboflavin synthase complex: shapes and functions of a highly variable enzyme system (2013), FEBS J., 280, 2537-2563.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6,7-dimethyl-8-(1-D-ribityl)lumazine Bacillus subtilis
-
riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
?
6,7-dimethyl-8-(1-D-ribityl)lumazine Methanothermobacter thermautotrophicus
-
riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
?
6,7-dimethyl-8-(1-D-ribityl)lumazine Methanocaldococcus jannaschii
-
riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-
Methanocaldococcus jannaschii
-
-
-
Methanothermobacter thermautotrophicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6,7-dimethyl-8-(1-D-ribityl)lumazine
-
Bacillus subtilis riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
?
6,7-dimethyl-8-(1-D-ribityl)lumazine
-
Methanothermobacter thermautotrophicus riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
?
6,7-dimethyl-8-(1-D-ribityl)lumazine
-
Methanocaldococcus jannaschii riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
?

Subunits

Subunits Comment Organism
homopentamer
-
Methanocaldococcus jannaschii
homotrimer
-
Bacillus subtilis
homotrimer
-
Methanothermobacter thermautotrophicus

Synonyms

Synonyms Comment Organism
lumazine synthase/riboflavin synthase complex
-
Bacillus subtilis
lumazine synthase/riboflavin synthase complex
-
Methanothermobacter thermautotrophicus
lumazine synthase/riboflavin synthase complex
-
Methanocaldococcus jannaschii