Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
DedolPP synthase | - |
Homo sapiens |
dehydrodolichyl diphosphate synthase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | dehydrodolichyl diphosphate synthase catalyzes the sequential condensation of isopentenyl diphosphate with farnesyl diphosphate to synthesize dehydrodolichyl diphosphate, a biosynthetic precursor for dolichol which plays an important role as a sugar-carrier lipid in the biosynthesis of glycoprotein in eukaryotic cells. Identification of a specific interaction of human dehydrodolichyl diphosphate synthase with the NiemannPick Type C2 protein (NPC2/HE1), whose defects cause NiemannPick type C2 disease | Homo sapiens |