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Literature summary for 2.5.1.86 extracted from

  • Kolly, G.S.; Boldrin, F.; Sala, C.; Dhar, N.; Hartkoorn, R.C.; Ventura, M.; Serafini, A.; McKinney, J.D.; Manganelli, R.; Cole, S.T.
    Assessing the essentiality of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants (2014), Mol. Microbiol., 92, 194-211.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2Z,6E)-farnesyl diphosphate + isopentenyl diphosphate Mycobacterium tuberculosis
-
diphosphate + trans,octacis-decaprenyl diphosphate
-
?
(2Z,6E)-farnesyl diphosphate + isopentenyl diphosphate Mycobacterium tuberculosis H37Rv
-
diphosphate + trans,octacis-decaprenyl diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WFF7
-
-
Mycobacterium tuberculosis H37Rv P9WFF7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2Z,6E)-farnesyl diphosphate + isopentenyl diphosphate
-
Mycobacterium tuberculosis diphosphate + trans,octacis-decaprenyl diphosphate
-
?
(2Z,6E)-farnesyl diphosphate + isopentenyl diphosphate
-
Mycobacterium tuberculosis H37Rv diphosphate + trans,octacis-decaprenyl diphosphate
-
?

Synonyms

Synonyms Comment Organism
Rv2361c locus name Mycobacterium tuberculosis

General Information

General Information Comment Organism
malfunction Rv2361gene deletion is bactericidal in vitro Mycobacterium tuberculosis