Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.83 extracted from

  • Yoshida, I.; Koyama, T.; Ogura, K.
    Dynamic Interaction between Components of Hexaprenyl Diphosphate Synthase from Micrococcus luteus BP-26 (1987), Biochemistry, 26, 6840-6845.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Micrococcus luteus O66127 and O66129 O66127: component A of hexaprenyl diphosphate synthase, O66129: component B of hexaprenyl diphosphate synthase
-
Micrococcus luteus BP-26 O66127 and O66129 O66127: component A of hexaprenyl diphosphate synthase, O66129: component B of hexaprenyl diphosphate synthase
-

Purification (Commentary)

Purification (Comment) Organism
purification of component A, purification of component B Micrococcus luteus

Reaction

Reaction Comment Organism Reaction ID
(2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate mechanism: farnesyl diphosphate binds to the components of the enzyme (A and B) to form an aggregate, A-B-(farnesyl diphosphate)-Mg2+, which probably represents an intermediary state of enzyme catalysis Micrococcus luteus

Subunits

Subunits Comment Organism
? x * 18000-49000 (component B) + x * 13000-24000 (component A), gel filtration Micrococcus luteus