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Literature summary for 2.5.1.67 extracted from

  • Xu, H.; Lybrand, D.; Bennewitz, S.; Tissier, A.; Last, R.L.; Pichersky, E.
    Production of trans-chrysanthemic acid, the monoterpene acid moiety of natural pyrethrin insecticides, in tomato fruit (2018), Metab. Eng., 47, 271-278 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
synthesis construction of the trans-chrysanthemic acid biosynthetic pathway in tomato fruits by expressing the chrysanthemyl diphosphate synthase gene, as well as an alcohol dehydrogenease (ADH) gene and aldehyde dehydrogenase (ALDH) gene from a wild tomato species, all under the control of the PG promoter. Trangenic tomato fruits show a concentration of trans-chrysanthemic acid that is about 1.7fold higher (by weight) than the levels of lycopene present in non-transgenic fruit, the level of lycopene in the transgenic plants is reduced by 68%. Ninety seven percent of the diverted DMAPP is converted to trans-chrysanthemic acid, but 62% of this acid is further glycosylated Tanacetum cinerariifolium

Organism

Organism UniProt Comment Textmining
Tanacetum cinerariifolium P0C565
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