Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
isoform CysM | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | specificity of CysM for its amino acid substrate is more than 500-fold greater for O-phospho-L-serine than for O-acetyl-L-serine. Specificity of CysM for this physiological sulfide equivalent, sulfur carrier protein CysO-COSH, is more than 3 orders of magnitude greater than that for bisulfide. CysM active site with the bound aminoacrylate intermediate is protected from solvent and that binding of CysO-COSH produces a conformational change allowing rapid sulfur transfer | Mycobacterium tuberculosis | ? | - |
? | |
O-acetyl-L-serine + hydrogen sulfide | - |
Mycobacterium tuberculosis | L-cysteine + acetate | - |
? | |
O3-phospho-L-serine + hydrogen sulfide | - |
Mycobacterium tuberculosis | L-cysteine + phosphate | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.025 | - |
O3-acetyl-L-serine | formation of the aminoacrylate intermediate | Mycobacterium tuberculosis | |
17 | - |
O3-phospho-L-serine | formation of the aminoacrylate intermediate | Mycobacterium tuberculosis |