Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-bromoporphobilinogen | - |
Arabidopsis thaliana | |
Ag2+ | 1 mM AgCl2, 90% inhibition | Arabidopsis thaliana | |
Cd2+ | 0.1 mM CdCl2, 55% inhibition | Arabidopsis thaliana | |
Co2+ | 0.1 mM CoCl2, 95% inhibition | Arabidopsis thaliana | |
Cu2+ | 1 mM CuSO4, 66% inhibition | Arabidopsis thaliana | |
Hg2+ | 0.1 mm HgCl2, 76% inhibition | Arabidopsis thaliana | |
hydroxylamine | - |
Arabidopsis thaliana | |
K+ | at high concentrations | Arabidopsis thaliana | |
additional information | - |
Arabidopsis thaliana | |
Na+ | at high concentrations | Arabidopsis thaliana | |
NH4+ | - |
Arabidopsis thaliana | |
Zn2+ | 1 mM ZnCl2, 78% inhibition | Arabidopsis thaliana |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.017 | - |
porphobilinogen | - |
Arabidopsis thaliana |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
31000 | - |
gel filtration | Arabidopsis thaliana |
35000 | - |
1 * 35000, SDS-PAGE | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
porphobilinogen | Arabidopsis thaliana | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
Columbia | - |
Purification (Comment) | Organism |
---|---|
- |
Arabidopsis thaliana |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Arabidopsis thaliana | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Arabidopsis thaliana |
0.073 | - |
- |
Arabidopsis thaliana |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4 porphobilinogen | in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 | Arabidopsis thaliana | uroporphyrinogen III + 4 NH3 | - |
? | |
4 porphobilinogen + H2O | - |
Arabidopsis thaliana | hydroxylmethylbilane + 4 NH3 | 1-hydroxymethylbilane, highly unstable | ? | |
porphobilinogen | - |
Arabidopsis thaliana | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 35000, SDS-PAGE | Arabidopsis thaliana |
Synonyms | Comment | Organism |
---|---|---|
porphobilinogen deaminase | - |
Arabidopsis thaliana |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
70 | - |
10 min, heat-stable up to 70°C | Arabidopsis thaliana |
80 | - |
10 min, 40% loss of activity | Arabidopsis thaliana |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.7 | 8.5 | - |
Arabidopsis thaliana |
8 | - |
- |
Arabidopsis thaliana |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 10 | pH 6.0: about 15% of maximal activity, pH 10.0: 25% of maximal activity | Arabidopsis thaliana |