Literature summary for 2.5.1.6 extracted from

Wang, J.; Zhu, Z.H.; Yang, H.B.; Zhang, Y.; Zhao, X.N.; Zhang, M.; Liu, Y.B.; Xu, Y.Y.; Lei, Q.Y.
Cullin 3 targets methionine adenosyltransferase IIalpha for ubiquitylation-mediated degradation and regulates colorectal cancer cell proliferation (2016), FEBS J., 283, 2390-2402 .

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General Stability

General Stability	Organism
Cullin 3 (CUL3) targets methionine adenosyltransferase IIa (MAT IIalpha) and promotes its proteasomal degradation through the ubiquitylation-mediated pathway	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P31153	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
LS-174T cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
MAT IIalpha	-	Homo sapiens
methionine adenosyltransferase IIalpha	-	Homo sapiens

General Information

General Information	Comment	Organism
metabolism	methionine adenosyltransferase IIalpha (MAT IIalpha) is a key enzyme in methionine metabolism and is associated with uncontrolled cell proliferation in cancer	Homo sapiens
physiological function	methionine adenosyltransferase IIalpha (MAT IIalpha) is a key enzyme in methionine metabolism and is associated with uncontrolled cell proliferation in cancer	Homo sapiens

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Release 2023.1 (January 2023)