Literature summary for 2.5.1.6 extracted from

Sun, M.; Guo, H.; Lu, G.; Gu, J.; Wang, X.; Zhang, X.E.; Deng, J.
Lysine acetylation regulates the activity of Escherichia coli S-adenosylmethionine synthase (2016), Acta Biochim. Biophys. Sin. (Shanghai), 48, 723-731 .

Search for more literature for 2.5.1.6

Cloned(Commentary)

Cloned (Comment)	Organism
-	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + L-methionine + H2O	Escherichia coli	-	phosphate + diphosphate + S-adenosyl-L-methionine	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P0A817	W3110, a laboratory strain of Escherichia coli K-12	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
acylation	12 lysine residues of the protein are acetylated. Acetylation lead to a decrease in its enzymatic activity, which could be reversed by CobB deacetylation. Lysine acetylation regulates the activity of the enzyme	Escherichia coli

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-methionine + H2O	-	Escherichia coli	phosphate + diphosphate + S-adenosyl-L-methionine	-	?

Synonyms

Synonyms	Comment	Organism
adenosylmethionine synthase	-	Escherichia coli
MAT	-	Escherichia coli

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Release 2023.1 (January 2023)