Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.6 extracted from

  • Garcia-Estrada, C.; Perez-Pertejo, Y.; Ordonez, D.; Balana-Fouce, R.; Reguera, R.M.
    Analysis of genetic elements regulating the methionine adenosyltransferase gene in Leishmania infantum (2007), Gene, 389, 163-173.
    View publication on PubMed
Search for more literature for 2.5.1.6

Activating Compound

Activating Compound Comment Organism Structure
cycloheximide cycloheximide inhibition of protein synthesis increases isozyme MAT2 mRNA level in the logarithmic phase only, an indication that the gene is regulated in promastigotes at the posttranscriptional level by protein factors that targets the transcript for degradation Leishmania infantum

Organism

Organism UniProt Comment Textmining
Leishmania infantum
-
-
-
Leishmania infantum LEM75
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
promastigote
-
 Leishmania infantum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + H2O
-
 Leishmania infantum phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?
ATP + L-methionine + H2O
-
 Leishmania infantum LEM75 phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?

Synonyms

Synonyms Comment Organism
MAT2
-
 Leishmania infantum
S-adenosyl-Lmethionine synthetase
-
 Leishmania infantum

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Leishmania infantum