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Literature summary for 2.5.1.6 extracted from

  • Kutty, G.; Hernandez-Novoa, B.; Czapiga, M.; Kovacs, J.A.
    Pneumocystis encodes a functional S-adenosylmethionine synthetase gene (2008), Eukaryot. Cell, 7, 258-267.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.6

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strain BL21(DE3) RIL Pneumocystis jirovecii
expressed in Escherichia coli strain BL21(DE3) RIL Pneumocystis murina
expressed in Escherichia coli strain BL21(DE3) RIL Pneumocystis carinii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 SDS-PAGE Pneumocystis jirovecii
45000
-
 SDS-PAGE Pneumocystis murina
45000
-
 SDS-PAGE Pneumocystis carinii

Organism

Organism UniProt Comment Textmining
Pneumocystis carinii B0YIL6
-
-
Pneumocystis jirovecii B0YIL4
-
-
Pneumocystis murina B0YIL2
-
-

Renatured (Commentary)

Renatured (Comment) Organism
in 50 mM Tris-HCl (pH 8.0), 10 mM MgSO4, and 10 mM dithiothreitol Pneumocystis jirovecii
in 50 mM Tris-HCl (pH 8.0), 10 mM MgSO4, and 10 mM dithiothreitol Pneumocystis murina
in 50 mM Tris-HCl (pH 8.0), 10 mM MgSO4, and 10 mM dithiothreitol Pneumocystis carinii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + H2O
-
 Pneumocystis jirovecii phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?
ATP + L-methionine + H2O
-
 Pneumocystis murina phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?
ATP + L-methionine + H2O
-
 Pneumocystis carinii phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?

Synonyms

Synonyms Comment Organism
AdoMet synthetase
-
 Pneumocystis jirovecii
AdoMet synthetase
-
 Pneumocystis murina
AdoMet synthetase
-
 Pneumocystis carinii
S-adenosylmethionine synthetase
-
 Pneumocystis jirovecii
S-adenosylmethionine synthetase
-
 Pneumocystis murina
S-adenosylmethionine synthetase
-
 Pneumocystis carinii

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Pneumocystis jirovecii
ATP
-
 Pneumocystis murina
ATP
-
 Pneumocystis carinii