Literature summary for 2.5.1.6 extracted from

Hote, P.T.; Sahoo, R.; Jani, T.S.; Ghare, S.S.; Chen, T.; Joshi-Barve, S.; McClain, C.J.; Barve, S.S.
Ethanol inhibits methionine adenosyltransferase II activity and S-adenosylmethionine biosynthesis and enhances caspase-3-dependent cell death in T lymphocytes: relevance to alcohol-induced immunosuppression (2007), J. Nutr. Biochem., 19, 384-391.

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Inhibitors

Inhibitors	Comment	Organism	Structure
cycloleucine	1-aminocyclopentane-1-carboxylic acid, specific MAT inhibitor	Homo sapiens
ethanol	25 mM ethanol substantially decreases the enzymatic activity of MAT II	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P31153	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
JURKAT cell	-	Homo sapiens	-
T-lymphocyte	T helper CD4+ lymphocyte	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-methionine + H2O	-	Homo sapiens	phosphate + diphosphate + S-adenosyl-L-methionine	-	?

Synonyms

Synonyms	Comment	Organism
MAT II	-	Homo sapiens
methionine adenosyltransferase II	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens

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Release 2023.1 (January 2023)