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Literature summary for 2.5.1.48 extracted from

  • Loizeau, K.; Gambonnet, B.; Zhang, G.F.; Curien, G.; Jabrin, S.; Van Der Straeten, D.; Lambert, W.E.; Rebeille, F.; Ravanel, S.
    Regulation of one-carbon metabolism in Arabidopsis: the N-terminal regulatory domain of cystathionine gamma-synthase is cleaved in response to folate starvation (2007), Plant Physiol., 145, 491-503.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification during an initial period of folate starvation, S-adenosyl-Met and Met pools decline, but are further restored to typical levels. Re-establishment of Met and S-adenosyl-Met homeostasis is concomitant with the removal of 92 amino acids at the N terminus of cystathionine gamma-synthase. Processing is specifically associated with perturbation of the folates pool and involves chloroplastic serine-type proteases Arabidopsis thaliana