Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-cycloserine | 82% loss of activity at 5 mM | Salmonella enterica subsp. enterica serovar Typhimurium | |
NH2OH | 97% loss of activity at 10 mM | Salmonella enterica subsp. enterica serovar Typhimurium | |
S-sulfocysteine | 26% loss of activity at 5 mM | Salmonella enterica subsp. enterica serovar Typhimurium | |
Semicarbazide | 60% loss of activity at 1 mM | Salmonella enterica subsp. enterica serovar Typhimurium |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.6 | - |
H2S | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
7.1 | - |
O-acetyl-L-Ser | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
29000 | - |
2 * 29000, SDS-PAGE | Salmonella enterica subsp. enterica serovar Typhimurium |
55000 | - |
cysteine synthase B, gel filtration | Salmonella enterica subsp. enterica serovar Typhimurium |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-acetyl-L-Ser + sulfide | Salmonella enterica subsp. enterica serovar Typhimurium | involved in thiosulfate assimilation | L-Cys + acetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
S-sulfocysteine synthase is identical with cysteine synthase B | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
303 | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-acetyl-L-Ser + H2S | - |
Salmonella enterica subsp. enterica serovar Typhimurium | L-Cys + acetate | - |
? | |
O-acetyl-L-Ser + methyl mercaptan | - |
Salmonella enterica subsp. enterica serovar Typhimurium | S-methylcysteine + acetate | - |
? | |
O-acetyl-L-Ser + sulfide | involved in thiosulfate assimilation | Salmonella enterica subsp. enterica serovar Typhimurium | L-Cys + acetate | - |
? | |
O-acetyl-L-Ser + thiosulfate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | S-sulfocysteine + sodium acetate | - |
? | |
O-acetyl-L-serine | - |
Salmonella enterica subsp. enterica serovar Typhimurium | L-cysteine + acetate | - |
? | |
O-acetyl-L-serine + thiosulfate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | S-sulfo-L-cysteine + acetate + H+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 29000, SDS-PAGE | Salmonella enterica subsp. enterica serovar Typhimurium |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
65 | - |
5 min, unstable above | Salmonella enterica subsp. enterica serovar Typhimurium |
77 | - |
5 min, complete loss of activity | Salmonella enterica subsp. enterica serovar Typhimurium |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Salmonella enterica subsp. enterica serovar Typhimurium |