Literature summary for 2.5.1.46 extracted from

Huang, J.K.; Tsai, S.; Huang, G.H.; Sershon, V.C.; Alley, A.M.; Wen, L.
Molecular cloning of bovine eIF5A and deoxyhypusine synthase cDNA (2004), DNA Seq., 15, 26-32.

Search for more literature for 2.5.1.46

Cloned(Commentary)

Cloned (Comment)	Organism
-	Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[eIF5A-precursor]-lysine + spermidine	Bos taurus	deoxyhypusine synthase is the first of the two enzymes that catalyze the maturation of eukaryotic initiation factor 5A. Synthesis of hypusine is essential for the function of eIF5A in eukaryotic cell proliferation and survival	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	Q6EWQ6	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
testis	-	Bos taurus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[eIF5A-precursor]-lysine + spermidine	deoxyhypusine synthase is the first of the two enzymes that catalyze the maturation of eukaryotic initiation factor 5A. Synthesis of hypusine is essential for the function of eIF5A in eukaryotic cell proliferation and survival	Bos taurus	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?

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Release 2023.1 (January 2023)