KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Senecio vernalis | |
0.0013 | - |
[eIF5A-precursor]-L-lysine | - |
Senecio vernalis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
41000 | - |
x * 41000, SDS-PAGE | Senecio vernalis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[eIF5A-precursor]-lysine + spermidine | Senecio vernalis | posttranslational activation of the initiation factor 5A | [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Senecio vernalis | Q9SC14 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Senecio vernalis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
homospermidine + putrescine | - |
Senecio vernalis | homospermidine + ? | - |
? | |
spermidine + putrescine | - |
Senecio vernalis | homospermidine + ? | - |
? | |
[eIF5A-precursor]-L-lysine + spermidine | - |
Senecio vernalis | [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine | - |
? | |
[eIF5A-precursor]-lysine + spermidine | - |
Senecio vernalis | [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine | i.e. [eIF5A-precursor]-N6-(4-aminobutyl)lysine | ? | |
[eIF5A-precursor]-lysine + spermidine | posttranslational activation of the initiation factor 5A | Senecio vernalis | [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 41000, SDS-PAGE | Senecio vernalis |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0022 | - |
[eIF5A-precursor]-L-lysine | + spermidine | Senecio vernalis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.3 | - |
glycine-NaOH buffer | Senecio vernalis |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
8.8 | 9.9 | pH 8.8: about 35% of maximal activity, pH 9.9: about 60% of maximal activity | Senecio vernalis |