Literature summary for 2.5.1.46 extracted from

Lee, Y.B.; Joe, Y.A.; Wolff, E.C.; Dimitriadis, E.K.; Park, M.H.
Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor (1999), Biochem. J., 340, 273-281.

No PubMed abstract available

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[eIF5A-precursor]-lysine + spermidine	-	Homo sapiens	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	i.e. [eIF5A-precursor]-N6-(4-aminobutyl)lysine	?

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	not dependent on NAD+ for binding of eIF5A	Homo sapiens

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Release 2023.1 (January 2023)