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Literature summary for 2.5.1.45 extracted from

  • Böttcher, F.; Ober, D.; Hartmann, T.
    Biosynthesis of pyrrolizidine alkaloids: putrescine and spermidine are essential substrates of enzymatic homospermidine formation (1994), Can. J. Chem., 72, 80-85.
No PubMed abstract available
Search for more literature for 2.5.1.45

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.012
-
 spermidine at 0.1 mM putrescine Eupatorium cannabinum
0.015
-
 putrescine at 0.1 mM spermidine Eupatorium cannabinum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
putrescine + spermine Eupatorium cannabinum
-
 sym-homospermine + propane-1,3-diamine
-
 ?

Organism

Organism UniProt Comment Textmining
Eupatorium cannabinum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Eupatorium cannabinum

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Eupatorium cannabinum
-
tissue culture
-
 Eupatorium cannabinum
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0006
-
-
 Eupatorium cannabinum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
putrescine + spermidine
-
 Eupatorium cannabinum N-(4-aminobutyl)butane-1,4-diamine + propane-1,3-diamine
-
 ?
putrescine + spermine
-
 Eupatorium cannabinum sym-homospermine + propane-1,3-diamine
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Eupatorium cannabinum
NADH
-
 Eupatorium cannabinum