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Literature summary for 2.5.1.39 extracted from

  • Okada, K.; Ohara, K.; Yazaki, K.; Nozaki, K.; Uchida, N.; Kawamukai, M.; Nojiri, H.; Yamane, H.
    The AtPPT1 gene encoding 4-hydroxybenzoate polyprenyl diphosphate transferase in ubiquinone biosynthesis is required for embryo development in Arabidopsis thaliana (2004), Plant Mol. Biol., 55, 567-577.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene PPT1, DNA and amino acid sequence determination and analysis, functional expression in and complementation of Saccharomyces cerevisiae and Schizosaccharomyces pombe enzyme null mutant cells, expression as GFP-fusion protein in Arabidopsis plants Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information gene disruption in Arabidopsis leads to arrest of embryo development at an early stage of zygotic embryogenesis Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion enzyme contains an N-terminal mitochondrial targeting sequence Arabidopsis thaliana 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana key enzyme in biosynthesis of ubiquinone, the enzyme is required for embryo development ?
-
?
solanesyl diphosphate + 4-hydroxybenzoate Arabidopsis thaliana
-
diphosphate + nonaprenyl-4-hydroxybenzoate
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q93YP7 gene PPT1
-

Source Tissue

Source Tissue Comment Organism Textmining
bud young Arabidopsis thaliana
-
embryo
-
Arabidopsis thaliana
-
flower
-
Arabidopsis thaliana
-
leaf low expression level Arabidopsis thaliana
-
additional information expression pattern Arabidopsis thaliana
-
ovary with developing embryo Arabidopsis thaliana
-
root low expression level Arabidopsis thaliana
-
stem low expression level Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranyl diphosphate + 4-hydroxybenzoate
-
Arabidopsis thaliana diphosphate + 3-geranyl-4-hydroxybenzoate
-
?
additional information key enzyme in biosynthesis of ubiquinone, the enzyme is required for embryo development Arabidopsis thaliana ?
-
?
additional information enzyme shows broad substrate specificity in terms of prenyl substrates Arabidopsis thaliana ?
-
?
solanesyl diphosphate + 4-hydroxybenzoate
-
Arabidopsis thaliana diphosphate + nonaprenyl-4-hydroxybenzoate
-
?

Synonyms

Synonyms Comment Organism
4-hydroxybenzoate polyprenyl diphosphate transferase
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Arabidopsis thaliana
4HPT
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Arabidopsis thaliana