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Literature summary for 2.5.1.29 extracted from
- Structural characterization of geranylgeranyl pyrophosphate synthase GACE1337 from the hyperthermophilic archaeon Geoglobus acetivorans (2018), Extremophiles, 22, 877-888 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpressed in Escherichia coli | Geoglobus acetivorans |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| hanging-drop vapor-diffusion at 37°C. The three-dimensional structure of determined by X-ray diffraction to 2.5 A resolution | Geoglobus acetivorans |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 75000 | - |
gel filtration | Geoglobus acetivorans |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate | Geoglobus acetivorans | - |
diphosphate + geranylgeranyl diphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Geoglobus acetivorans | A0A0A7GEY4 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Geoglobus acetivorans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate | - |
Geoglobus acetivorans | diphosphate + geranylgeranyl diphosphate | - |
? | |
| (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate | the enzyme produces geranylgeranyl pyrophosphate as a major product and of farnesyl pyrophosphate in smaller amounts | Geoglobus acetivorans | diphosphate + geranylgeranyl diphosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Geoglobus acetivorans |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| geranylgeranyl pyrophosphate synthase GACE1337 | - |
Geoglobus acetivorans |
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Release 2023.1 (January 2023)
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