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Literature summary for 2.5.1.27 extracted from

  • Chu, H.M.; Chen, F.Y.; Ko, T.P.; Wang, A.H.
    Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates (2010), FEBS Lett., 584, 4083-4088.
    View publication on PubMed
Search for more literature for 2.5.1.27

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Humulus lupulus the plant AIPT predominantly uses ATP or ADP as the isopentenyl acceptor ?
-
 ?

Organism

Organism UniProt Comment Textmining
Humulus lupulus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dimethylallyl diphosphate + ATP
-
 Humulus lupulus diphosphate + N6-(dimethylallyl)adenosine triphosphate
-
 ?
dimethylallyl diphosphate + P1,P3-bis(5'-adenosyl)triphosphate
-
 Humulus lupulus ?
-
 ?
dimethylallyl diphosphate + P1,P4-bis(5'-adenosyl)tetraphosphate
-
 Humulus lupulus ?
-
 ?
dimethylallyl diphosphate + P1,P5-bis(5'-adenosyl)pentaphosphate
-
 Humulus lupulus ?
-
 ?
dimethylallyl diphosphate + P1,P6-bis(5'-adenosyl)hexaphosphate
-
 Humulus lupulus ?
-
 ?
additional information the plant AIPT predominantly uses ATP or ADP as the isopentenyl acceptor Humulus lupulus ?
-
 ?
additional information no activity with NAD+, NADP+, and FAD Humulus lupulus ?
-
 ?

Synonyms

Synonyms Comment Organism
adenylate isopentenyltransferase
-
 Humulus lupulus
AIPT
-
 Humulus lupulus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Humulus lupulus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5 7 assay at Humulus lupulus

General Information

General Information Comment Organism
metabolism cytokinins are important adenine-base phytohormones which promote cell division and their biosynthesis has two pathways depending on different substrates. The first pathway begins with the transfer of isopentenyl group from dimethylallyl diphosphate to the N6-amino group of AMP, ADP or ATP by adenylate isopentenyltransferase, AIPT Humulus lupulus
physiological function the isopentenyltransferase reaction is the key rate-limiting step in cytokinin biosynthesis that transfers the isopentenyl group from dimethylallyl diphosphate to the N6-amino group of adenine Humulus lupulus