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Literature summary for 2.5.1.26 extracted from

  • Zomer, A.W.M.; de Weerd, W.F.C.; Langeveld, J.; van den Bosch, H.
    Ether lipid synthesis: purification and identification of alkyl dihydroxyacetone phosphate synthase from guinea-pig liver (1993), Biochim. Biophys. Acta, 1170, 189-196.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.068
-
Palmitoyldihydroxyacetone phosphate cosubstrate hexadecanol Cavia porcellus
0.072
-
hexadecanol cosubstrate palmitoyldihydroxyacetone phosphate Cavia porcellus
0.1
-
hexadecanol cosubstrate hexadecyldihydroxyacetone phosphate Cavia porcellus
0.115
-
Hexadecyldihydroxyacetone phosphate cosubstrate hexadecanol, 0.4 mM Cavia porcellus
0.192
-
Hexadecyldihydroxyacetone phosphate cosubstrate hexadecanol, 0.05 mM Cavia porcellus

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome membrane Cavia porcellus 5777
-
peroxisome membrane Homo sapiens 5777
-
peroxisome membrane Rattus norvegicus 5777
-
peroxisome membrane Bos taurus 5777
-
peroxisome membrane Pan troglodytes 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
65000
-
gel filtration, phosphocellulose chromatography Cavia porcellus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Cavia porcellus
-
-
-
Homo sapiens
-
-
-
Pan troglodytes
-
chimpanzee
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Cavia porcellus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-
brain
-
Rattus norvegicus
-
kidney
-
Bos taurus
-
liver
-
Cavia porcellus
-
liver
-
Homo sapiens
-
liver
-
Rattus norvegicus
-
liver
-
Pan troglodytes
-
placenta low activity Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.35
-
-
Cavia porcellus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-O-hexadecyldihydroxyacetone phosphate + hexadecanol
-
Cavia porcellus long-chain acid anion + 1-O-hexadecyldihydroxyacetone phosphate
-
?
palmitoyldihydroxyacetone phosphate + hexadecanol
-
Cavia porcellus 1-O-hexadecyldihydroxyacetone phosphate + palmitate
-
?
palmitoyldihydroxyacetone phosphate + hexadecanol
-
Rattus norvegicus 1-O-hexadecyldihydroxyacetone phosphate + palmitate
-
?

Subunits

Subunits Comment Organism
monomer 1 * 65000, SDS-PAGE Cavia porcellus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
Cavia porcellus
7.5
-
-
Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
6.5 9 pH 6.5: about 50% of maximum activity, pH 9.0: about 30% of maximum activity Cavia porcellus