Cloned (Comment) | Organism |
---|---|
the truncated SmSQS2 in which 28 amino acids are deleted from the carboxy terminus was expressed as GST-Tag fusion protein in Escherichia coli BL21 (DE3) | Salvia miltiorrhiza |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | membrane-bound | Salvia miltiorrhiza | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 (2E,6E)-farnesyl diphosphate + NADPH + H+ | Salvia miltiorrhiza | the enzyme catalyzes the first dedicated step in the biosynthesis of sterols and other triterpenoids | squalene + 2 diphosphate + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Salvia miltiorrhiza | M4H1H3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | gene expression level is higher in roots as compared to the leaves | Salvia miltiorrhiza | - |
root | gene expression level is higher in roots as compared to the leaves | Salvia miltiorrhiza | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 (2E,6E)-farnesyl diphosphate + NADPH + H+ | overall reaction | Salvia miltiorrhiza | squalene + 2 diphosphate + NADP+ | - |
? | |
2 (2E,6E)-farnesyl diphosphate + NADPH + H+ | the enzyme catalyzes the first dedicated step in the biosynthesis of sterols and other triterpenoids | Salvia miltiorrhiza | squalene + 2 diphosphate + NADP+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 66460, SDS-PAGE | Salvia miltiorrhiza |
Synonyms | Comment | Organism |
---|---|---|
SQS2 | - |
Salvia miltiorrhiza |
squalene synthase 2 | - |
Salvia miltiorrhiza |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Salvia miltiorrhiza |
Organism | Comment | Expression |
---|---|---|
Salvia miltiorrhiza | gene expression level is higher in roots as compared to the leaves, and is up-regulated upon YEC Ag+ treatment | up |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme catalyzes the first dedicated step in the biosynthesis of sterols and other triterpenoids | Salvia miltiorrhiza |