Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(trans-4-stilbenyl)-4-methyl-morpholin-2-ol | - |
Rattus norvegicus | |
3-(trans-4-stilbenyl)octahydropyridino[2,1-c][1,4]oxazin-3-ol | - |
Rattus norvegicus | |
4-methyl-2-(3',5'-di-tert-butyl-4'-hydroxy-4-biphenyl)-3,4-dihydro-2H-1,4-benzothiazine-2-ol | - |
Rattus norvegicus | |
4-methyl-2-(4'-hydroxybiphenyl)-3,4-dihydro-2H-1,4-benzothiazin-2-ol | - |
Rattus norvegicus | |
4-methyl-2-(4'-trifluromethyl-4-biphenyl)-3,4-dihydro-2H-1,4-benzothiazine-2-ol | - |
Rattus norvegicus | |
4-methyl-2-phenyl-3,4-dihydro-2H-benzothiazin-2-ol | - |
Rattus norvegicus | |
4-methyl-2-phenyl-3,4-dihydro-2H-benzoxazin-2-ol | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 (2E,6E)-farnesyl diphosphate + NADPH + H+ | Rattus norvegicus | - |
squalene + 2 diphosphate + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q02769 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 (2E,6E)-farnesyl diphosphate + NADPH + H+ | - |
Rattus norvegicus | squalene + 2 diphosphate + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SQS | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0065 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-methyl-2-(3',5'-di-tert-butyl-4'-hydroxy-4-biphenyl)-3,4-dihydro-2H-1,4-benzothiazine-2-ol | |
0.007 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 2-(trans-4-stilbenyl)-4-methyl-morpholin-2-ol | |
0.0085 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-methyl-2-(4'-hydroxybiphenyl)-3,4-dihydro-2H-1,4-benzothiazin-2-ol | |
0.014 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-methyl-2-(4'-trifluromethyl-4-biphenyl)-3,4-dihydro-2H-1,4-benzothiazine-2-ol | |
0.028 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-methyl-2-phenyl-3,4-dihydro-2H-benzothiazin-2-ol | |
0.042 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 3-(trans-4-stilbenyl)octahydropyridino[2,1-c][1,4]oxazin-3-ol | |
0.05 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-methyl-2-phenyl-3,4-dihydro-2H-benzoxazin-2-ol |